FOR5130 ImmunoChick- Unravelling the avian immune response in the context of infection
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FOR5130 ImmunoChick- Unravelling the avian immune response in the context of infection

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The objective of ImmunoChick is to understand the avian immune system, focusing on the adaptive immune response and its interactions with the most relevant pathogens by developing and using novel technologies.The recently generated B and T cell knockout chickens offer unprecedented opportunities to investigate the interaction between different cell types of the immune system.

These tools are uniquely available to this group and will be used to address our overall objective in three specific aims:

  1. To determine the role of γδ T cells in the pathogenesis and vaccine protection
  2. To characterize αβ T cell knockout chickens and address the role of αβ T cells in pathogenesis
  3. Analysis of poorly characterized lymphocyte populations and development of novel reverse genetic systems

 

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